Kee Lab Publications:

Dias S, Xu W, McGregor S and B Kee. (2008) Transcriptional regulation of lymphocyte development. Curr. Opin. Genet. Dev. in press. Link

Dias S, Mansson R, Gurbuxani S, Sigvardsson M and BL Kee. (2008) E2A proteins promote development of lymphoid-primed multipotent progenitors. Immunity 29:217-227. Link

Boos MD, Ramirez K and BL Kee. (2008) Extrinsic and intrinsic regulation of early natural killer cell development. Immunol. Res. 40(3):193-207. Link.

Bhalla S, Spaulding C, Brumbaugh RL, Zagort DE, Massari ME, Murre C and BL Kee. (2008) Differential roles for the E2A activation domains in B lymphocytes and macrophages. J. Immunol. 180(3):1694-1703. Link.

Nutt SL and BL Kee. (2007) The transcriptional regulation of B cell lineage commitment. Immunity, 26(6):715-725. Link.

Spaulding C, Reschly, EJ, Zagort DE, Yashiro-Ohtani Y, Beverly LJ, Capobianco A, Pear WS and BL Kee. (2007) Notch1 co-opts lymphoid enhancer factor 1 for survival of murine T-cell lymphomas. Blood, 110(7):2650-2658. Epub Jun 21. Link.

Boos MD, Yokota Y, Eberl G and BL Kee (2007) Mature natural killer cell and lymphoid tissue-inducing cell development requires Id2-mediated suppression of E protein activity. J. Exp. Med. 204(5):1119-1125. Link.

Xu X and BL Kee. (2007) Growth factor independence 1b (Gfi1b) is an E2A target gene that modulates Gata3 in T cell lymphomas. Blood 109(10):4406-4414.  Link.

Reschly EJ, Spaulding C, Vilimas T, Graham WV, Brumbaugh RL, Aifantis I, Pear WS and BL Kee. (2006) Notch1 promotes survival of E2A-deficient T cell lymphomas through pre-T-cell receptor-dependent and -independent mechanisms. Blood 107(10):4115-5121. Link.

Kee BL (2005) Id3 induces growth arrest and caspase-2-dependent apoptosis in B lymphocyte progenitors. J. Immunol. 175:4518-4527. Link.

Osborne BA and BL Kee (2005) Lymphoid development: it's not 'all Greek to us' any more. Nat. Immunol. 6(2):119-123. Link.

Kee BL. (2005) Helix-loop-helix proteins in lymphocyte lineage determination. Cur. Top. Microbiol. Immunol. 290:15-29. Link.

Seet CS, Brumbaugh RL and BL Kee (2004) Early B cell factor promotes B lymphopoiesis with reduced interleukin 7 responsiveness in the absence of E2A. J. Exp. Med. 119(12):1689-1700. Link.

Kee BL, Bain G and C Murre. (2002) IL-7Ralpha and E47: independent pathways required for development of multipotent  lymphoid progenitors. (2002) EMBO J. 21:103-113. Link.



Collaborative Publications:

Welner RS, Pelayo R, Garrett KP, Chen X, Perry SS, Sun XH, Kee BL and PW Kincade. (2007) Interferon-producing killer dendritic cells  (IKDC) arise via a unique differentiation pathwaay from primitive c-kitHiCD6L+ lymphoid progenitors. Blood, 109(11):4825-4931. Link.

Vilimas T, Mascarenhas J, Palomero T, Mandal M, Buonamici S, Meng F, Thompson B, Spaulding C, Macaroun S, Alegre ML, Kee BL, Ferrando A, Miele L and I Aifantis. (2007) Targeting the NF-kappaB signaling pathway in Notch1-induced T-cell  leukemia. Nat. Med. 13(1):70-77. Link.

Nick McElhinny SA, Havener JM, Garcia-Diaz M, Juarez R, Bebenek K, Kee BL, Blanco L, Kunkel TA and DA Ramsden. (2005) A gradient of template dependence defines distinct biological roles for family X polymerases in nonhomologous end joining. Mol. Cell 19(3):357-366. Link.

Perkins EJ, Kee BL and DA Ramsden. (2004) Histone 3 lysine 4 methylation during the pre-B to immature B-cell transition. Nucleic Acids Res. 32(6):1942-1947. Link.